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Briefly, I think that this is one of the most important books so far of the twenty-first century. Viral is essentially a page plea to follow every lead as if we actually wanted to get to the bottom of things, and in particular, yes, to take the possibility of a lab leak a hell of a lot more seriously than was publicly permitted in Fortuitously, much of this shift already happened as the authors were writing the book, but in June I was still sneered at for discussing the lab leak hypothesis on this blog.

Viral is simultaneously a model of lucid, non-dumbed-down popular science writing and of cogent argumentation. If you read the book and your mind works anything like mine, be forewarned that you might come out agreeing with a lot of it. Very few scientists in history have faced that sort of psychic burden, perhaps not even the ones who built the atomic bomb.

Would you? Viral very wisely never tries to psychoanalyze Shi and Daszak. And one point Viral makes abundantly clear is that, if our goal is to prevent the next pandemic, then resolving the mystery of COVID actually matters less than one might think. This is because, whichever possibility—zoonotic spillover or lab leak—turns out to be the truth of this case, the other possibility would remain absolutely terrifying and would demand urgent action as well.

Read the book and see for yourself. As I wrote seven months ago, I now see my lack of courage on this as having been a personal failing. On another level, though, Viral is optimistic. You can follow any responses to this entry through the RSS 2. You can leave a response , or trackback from your own site. The zoonotic risks encountered by mankind moving further and further into new wilderness areas Amazon rainforest etc have been laid out in a number of popular science books since the 90s.

When authors put forth and portray a high degree of confidence in a theory that relies on features that are subsequently falsified by new evidence, the credibility of the theory and its advocates is undermined. A more fruitful question than whether or not it originated in a lab could be to consider how might we extend modeling of molecules and catalysts to simulating microorganisms, which could negate the need for running such a lab in the first place.

Call it a long term objective. That was never the biggest difficulty for an origin theory: the biggest difficulty was how it gets from the cave to Wuhan without being noticed anywhere else along the way. Matt Ridley is well-known amongst people in climate science discussion for spreading absolute bullshit with the backing of being in the House of Lords and also being a science writer.

Update: On a Hacker News thread about this post, Alina Chan herself points me to a recent Twitter thread of hers where she responds to the Laos paper. Briefly, Alina interprets the same new revelation through a completely different lens.

Thus, instead of:. It was an awful book. Without having followed the debate closely one could be forgiven for thinking the biased and omissions in this work were merely due to ignorance about the new research that came out while the book was being written. But Ridley and Chan were repeatedly supplied with pointers to new research that undermined their central claims, including being called out repeatedly by experts like Angie Rasmussen and Kristian Anderson.

As the preponderance of evidence in favor of zoonotic origin mounted, the authors obdurately stuck to their preconceived narrative, which was essentially repackaged DRASTIC claims.

But I will undoubtedly read with a more critical eye. J Allen Could you expand on what, specifically, was the new research that Chan and Ridley ignored that undermines their central claims? Michael Worobey, who was a supportive signatory on the letter urging further exploration of origins, found upon reanalysis that all of the index cases really do seem to cluster on the Huanan market, well across the river from WIV.

So you have to craft a pretty unlikely set of events to explain the absence of any more obvious nexus of cases around WIV that somehow instead exploded among some animal vendors across the river. I spent two decades doing synthetic biology work in immune cells, viruses, etc.

All of the synthetic metagenomic experiments ever outlined in grants eg. Even if for some perverse reason they used the previously known RAT13g, etc. May their reputations forever be blemished. Have you seen this article? Then last month a bunch of emails, uncovered by a lawsuit from the so-called White Coat Waste Project, returned the ball right back over the net.

They comprised an exchange between the American virus—hunting foundation, the EcoHealth Alliance and its funders in the US government. The scientists discussed collecting viruses from bats in eight countries including Burma, Vietnam, Cambodia and Laos between and But to avoid the complication of signing up local subcontractors to their grants in those countries, they promised to send the samples to a laboratory they already funded.

And where was this lab? The same Peter Daszak who funneled millions of dollars in US research grants specifically into coronavirus research in the WIV was the only US representative on the WHO task force investigating the origins of the virus, and when later asked if they got a look at that virus database that was taken offline, he said:. And we did not ask to see the data…. As you know, a lot of this work has been conducted with EcoHealth Alliance…. Btw, he was also the head of the Lancet investigation into the origins of Covid, later disbanded when people noticed.

Because the larger it is the more probable it becomes that it has to involve someone who is not that evil, or is more selfish than evil, and becomes a whistleblower.

Do you agree that this is not a good look? To my eye, the most striking aspect of the lab leak discourse is how the most intransigent and vocal zoonotic proponents are a particular type of scientist — virologists, a small specialized discipline comprised of people with a lot to lose professionally should a leak be proven. The second most intransigent and vocal proponents are journalists in their professional capacity trying to make people look like idiots.

My understanding is that in all previous serious viral outbreaks from animals, scientists were quickly able to trace the path the virus took through the animal populations by literally catching animals, testing them, and sequencing the virus.

Another thought is that, if covid was able to transmit itself so easily from animals to humans, and vice-versa, across long distances, then we should expect that the animal world is itself currently totally overflowing with covid contaminations and mutations.

That pool of the virus could be orders of magnitude bigger than in the human population. If the theory is indeed falsified, the credibility of the theory is undermined; the credibility of its advocates hinges upon their reaction to the new information. Not that I have much hope for humanity left, but that turning out to be true would end it.

Fortunately, the more expert sources which I read such as the Mike the Mad Biologist blog and its links seem to believe a natural source for the virus is far more likely than any form of lab-leak.

I stopped reading your post after the third paragraph and ordered the book. It sounds very good and deals with a subject that I really want to understand.

We know for a fact that WIV, like many other virology labs around the world, was and is collecting dangerous viruses and engineering them to make them even more dangerous. Virologists have been doing this with the noble goal of predicting which natural viruses have the potential to evolve to cause a pandemic, and thereby averting a pandemic.

To answer that question, it would obviously help to have full details about exactly which experiments WIV was doing on which viruses between and Incredibly, unbelievably, WIV has refused to divulge that information for the past two years. The lax precautions when collecting samples and low safety levels under which some of the viruses were handled in the lab make these scientists one of the highest-risk groups for a natural spillover in Wuhan.

In the months before the election there was a Republican talking point floating around that said: China is an existential threat to America, human freedom, etc, and Trump is the only person who can save us. This talking point even showed up in the comments of this blog. But the whole lab leak theory episode illustrates what a massive liability Trump is to American stability.

Suppose covid really did originate from a lab leak in China. If you were a Chinese official charged with manipulating public discourse in order to keep fingers pointed away from China, Trump would make your job much, much easier.

So to keep decent people from discussing the truth the lab leak , you just have to get the truth associated with Trump and his lunatic followers. When the president is a notorious liar, all discourse becomes poisoned with distrust, and that makes foreign manipulation easy.

Scott, thanks for the clarification. As I understand your reply, you are saying they were engineering viruses for the purpose of making them more understood and ultimately less dangerous. That being the case I would be more inclined personally to take them at their word that they were not working on the SC2 virus and did not leak it.

Not that my opinion matters worth a hill of beans in this crazy world, but it makes me feel a bit better that way, without influencing anything important. We can safely assume, rather than losing face, the PRC government will do anything to obfuscate the case of the -possible — origins of Covid This was already visible in the reaction to the warning by Dr Li Wenliang — the first to publicly warn about the virus — and who later died of it.

It is definitely not the case that all zoonotic outbreaks could be quickly traced to their origin. COVID is asymptomatic or mild in many people, but they can still spread it, so tracking down the first case is going to be harder. Nick Drozd Not only do I completely agree with you, I think your point holds much more generally. I sometimes wonder whether the wokes, who do things like baselessly denounce E. Wilson as a racist just days after death , are actually secret Trumpists trying to cause a conservative backlash.

Or conversely, whether the Trumpists are secret wokes trying to cause a liberal backlash. In fact, the terms refer to two completely different categories. On the one hand, we have the molecular origin of the virus, and on the other we have its introduction into the human population.

In this scenario, the WIV serves simply as a kind of vector for the spread of a naturally occurring virus. JimV They were , literally, making viruses more dangerous. As for taking the WIV researchers at their word—I mean, that was my first inclination too! Because of these astonishing omissions, my personal view is that alas, a lot of the goodwill they were initially due has now evaporated.

It has been very interesting to see what information gets presented by the mass media, even science journals, as pure fact and what real facts get selectively ignored or censored.

Kudos to Scott Aaronson for reading and reviewing the book despite all the bad press. Hopefully the truth will come out someday. Nick Drozd The fact remains that Trump was right to take the lab leak possibility seriously and liberals were wrong to reject it out of hand. All evidence must be soberly analyzed on its own merits, regardless of who brings it forward. Liberals failed this basic rule of rationality.

Labeling lab leak a conspiracy theory was a liberal rallying cry because Trump endorsed it. Many plausible speculations have been made and discarded, such as phlogiston. I believe the experts will continue to examine actual biological data , regardless of what anyone speculates. Personally, I find it plausible that the Chinese bureaucracy told the lab scientists to stop cooperating with reactionary foreign intruders their imagined words, not mine.

Also, I dimly remember reading an article years ago, where virologists?

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Brandon Marshall and Michael Spencer discuss what the future holds for Vic Fangio, which positions the Broncos should target in the offseason, and the biggest disappointments and surprises from this NFL season. Buccaneers tight end Rob Gronkowski shared his reaction to Antonio Brown's meltdown during Sunday's game vs. Instant takeaways from the loss in the Texas Bowl. Will the owner force the team to find another quarterback? Detroit coach Dan Campbell gave a great answer about how the Seahawks ended the win over his Lions in Week

Ferrari F1 Boss Defends Michael Masi After Abu Dhabi GP Row

Michael is a veteran technology writer who has been covering business and consumer-focused hardware and software for over a decade. The best iPhones in Read More. Cupertino may have taken slightly longer to add its third trillion, but it's an even more impressive accomplishment given the fact that it occurred during the COVID pandemic, while many companies are still struggling to maintain component supply chains. Apple's accomplishment was, justifiably, seen as the result of the continued success of its iPhone lines. While Apple does occasionally miss the mark with releases like the HomePod, it's far more likely to dominate any market segments it chooses to target. The Apple Watch's continued position atop the wearables market should be evidence enough of that. This knack for clinching product categories makes it likely that Apple's long-rumored augmented reality AR glasses will have an additive effect on its bottom line, something multiple sources expected to happen in Apple finds a brilliant way to make the iPhone 13 Pro exciting. Best iPhones : Which model is right for you?

‘The Cleaning Lady’ Review: Cliché Dirties Up Elodie Yung’s Confident Portrayal

By SportsDay Staff. Here are some highlights, edited for clarity:. I know he was looking forward to what free agency was going to bring, and hopefully right here in Dallas. I know we have our challenges here, but no one thinks more of Michael Gallup as a Dallas Cowboy than his teammates, than his coaching staff, than this organization.

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The interim tag was removed in November, but when players report back from the holiday break on Jan. Allvin gained Rutherford's trust by running the amateur scouting side in Pittsburgh for years and currently handles salary cap and collective bargaining agreement issues. Mayweather retired in but returned to defeat Conor McGregor in and improve his professional record to Find the best places within Vancouver. From local businesses to food to medical to legal services.

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Firefighters work to contain several home fires on the block of Pennsylvania Avenue, Tyrone on July 26, Altoona Mirror photo by Dan Isenberg. The explosion in Tyrone that killed one person and the death of Blair County Corrections Officer Rhonda Russell were voted the top local stories of by the Mirror newsroom. The news staff voted in December on the top stories from a ballot that included the most prominent news items from throughout the year. Flooding issues and job losses also made the Top 10 list. An explosion caused by a gas leak July 26 killed an elderly woman and injured several people on the block of Pennsylvania Avenue in downtown Tyrone.

Kristen Lopez. It certainly feels like a FOX series, with its flashy editing, gritty storyline, and adoration of clubs and opulence. When she witnesses a crime, the only means of looking indispensable is by offering to clean up the corpse and its aftermath. Yes and no.

Political reporter itssophiemorris. In a letter, shadow levelling up secretary Lisa Nandy demands Mr Gove release the criteria on which the decision was made, explain what steps were taken to ensure Tory councillors weren't lobbied, and prove taxpayers' money was protected at all times. The story said the government funds were applied for by Charleston Farmhouse - an independently run museum and art gallery within the grounds of Lord Gage's Firle Estate. The trust said the track needed repair works after "poor drainage" had corroded it.

The unique and challenging year that was , a year dominated again by the worldwide COVID pandemic, has drawn to a close. While the coronavirus stories took centre stage much of the year, there was still plenty of other news in the Parksville Qualicum Beach area. Town council, with Coun. Robert Filmer returning following a two-month medical leave of absence, endorsed Heather Svenson to be the chief election officer at the its regular council meeting on Wednesday, Feb. The year-old Parksville junior first dan black belt came across a virtual international competition online that sparked his interest and entered to compete in the Tbilisi Open Online Goju-Ryu Kata Tournament, hosted by the International Okinawan Goju-Ryu Karate-do Federation in Georgia. It took place Nov.

Larry Demery was convicted for the death of James Jordan, who was traveling from Charlotte to Wilmington when he stopped on the side of the road in Lumberton to take a nap. Demery and Daniel Green shot and killed him during a robbery. They also took his phone and NBA rings given to him by his son.